Dissociatives are drugs which reduce or block signals to the conscious mind from other parts of the brain. Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects.Many dissociatives have general depressant effects as well.
DXM is dextromethorphan. It is a legal cough suppressant found in many over-the-counter cough syrups. In high doses it acts as a "dissociative anaesthetic" like ketamine or PCP. A high dose will cause you to feel very spacey and "out of it," and you may lose motor control (your legs may feel wobbly, for example, or at very high doses you won't be able to move much at all). It can also produce audio and visual hallucinations, and can sometimes cause nausea and itchy skin.