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A psychedelic substance is a psychoactive drug whose primary action is to alter the cognition and perception of the mind. Psychedelics are part of a wider class of psychoactive drugs known as hallucinogens, which also includes related substances such as dissociatives and deliriants.

Use of the word "narcotic" to refer to any illegal or unlawfully possessed drug including marijuana and cocaine is common worldwide, although these substances are not considered narcotics in a medical context. In U.S. legal context, the term "narcotic" specifically refers to opium, opium derivatives, and their semi-synthetic or fully synthetic substitutes as well as cocaine and coca leaves.