Alcohol

One of the most popularly consumed substances in the world, alcohol is a euphoric sedative that produces social disinhibition.

Nicotine

Nicotine is the main psychoactive ingredient in tobacco, and is now frequently consumed alone in the form of vaping.

Ketamine

Ketamine is a short-acting dissociative used widely in medical practices as well as recreational settings.

Nitrous Oxide

Nitrous is a psychoactive gas that's frequently used in medical practice as well as in recreational settings. Its effects are dissociating and sedating.

Poppers

Sold as "shoe cleaner" or "room deodorizer," poppers are bottles containing nitrite fluids that are wafted (not ingested) as inhalants.

Heroin

Heroin, or diacetylmorphine, is an opiate derived from the opium poppy that produces a sense of calm, relaxation, and sedation.