Ketamine Bladder Damage – What You Need to Know

Using ketamine can be fun, and recent studies have shown it to have antidepressant effects. (1) But using it too often can damage your bladder and result in a serious condition known as Ketamine Bladder Syndrome (a.k.a. Ketamine Cystitis). Your bladder is a round sac behind your pelvic bone that holds urine. It is about the size of a grapefruit, but can stretch much larger when full. When ketamine and its metabolites enter the bladder, they damage the epithelial cells of the bladder lining.(2) (3) These umbrella-shaped cells are designed to contain the urine, but if they become too damaged, urine...